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(2018, December 1)

By working on distinct substrate proteins, DUBs play a role in several biological processes, including cell proliferation, differentiation, and apoptosis

Recently, it has been reported that combination of statins (atorvastatin, fluvastatin and simvastatin) and conventional chemotherapy (topotecan, paclitaxel and doxorubicin) acted synergistically to inhibit cell proliferation and to induce cytotoxicity in an aggressive natural killer cell leukemia (221)

In this chapter, we will explore the application possibilities of salicylic acid in combination with living biological organisms and the experiences gained with them

Among the molecular perturbations that high temperature induces in living cells is the accumulation of reactive oxygen species (ROS), which can damage macromolecules of the cell and perturb the cellular redox state

Sustained inflammatory activation can, in turn, promote hepatic stellate cell (HSC) activation and extracellular matrix deposition, thereby contributing to fibrogenesis