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This mechanism has been confirmed in both mouse models and human lymphoma, and demethylating drugs (e.g., 5-aza-2'-deoxycytidine) can restore Spry2 expression and suppress ERK activity (Frank et al., 2009[32])

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[DOI] [PMC free article] [PubMed] [Google Scholar] 86.Pinto J.V., Saraf G., Frysch C., Vigo D., Keramatian K., Chakrabarty T., Lam R.W., Kauer-SantAnna M., Yatham L.N

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Bulletin of the National Research Centre, 48 (1), 33

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