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Med Sci Sports Exerc 54(2):353368

GSH can also serve as a substrate for S-glutathionylation of proteins in the presence of small redox enzyme glutaredoxins (GRX), which also utilizes GSH as a cofactor ( Figure 1 )

The slope of the exposure-response relationship was much flatter (0.31 for males) than that of Ikeda et al

Micro-dosing addresses this concern by providing intermittent gentle stimulation rather than constant maximum activation

Wang B, Wu G, Zhou Z, Dai Z, Sun Y, Ji Y, Li W, Wang W, Liu C, Han F, Wu Z

Increased proteolytic degradation of aggregated polysaccharides and a rise in non-aggregated proteoglycans are early degenerative modifications in intervertebral discs (Zhang et al., 2021)