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Description

10.1016/j.bpj.2013.01.051 18 ChenS.LiaoC.HuangH.WeissT.Bellisent-FunelM.SetteF

2024;13:e2400125

The compound belongs to a class of short regulatory peptides investigated in experimental models exploring cellular longevity pathways, peptide signalling networks and molecular regulatory systems

Until well-designed human clinical trials are published, any claims about BPC-157s efficacy remain speculative

Previous studies demonstrated that different components in the p53/MDM2/ARF pathway, such as MDM2/MDM4 protein, negatively regulate the activity of p53 (6972)

Both respiratory tract function and histopathological effects were seen when animals were exposed to acrolein at levels of 0.5 mg/m 3 or more for 90 days