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DOSAGE AND ADMINISTRATION For Intramuscular administration: General: Twice daily 1 ml per 20 - 40 kg body weight for 3 days

They are not dietary supplements, drugs, or cosmetics and should only be handled by trained professionals in controlled laboratory environments

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Receptor Downregulation Findings and Study Design Implications A well-documented finding in the research literature is that continuous IGF-1 receptor activation leads to receptor downregulation after approximately four to six weeks, reducing cellular responsiveness to further stimulation

Discovery and Research Timeline Researchers identified the first estrogen-related receptor as an orphan nuclear receptor related to, but distinct from, classical estrogen receptors