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Description

Follow all applicable local regulations regarding research compounds.

Long-term consequences of NNMT inhibition are unknown Dosing is not established : No human dosing protocol has been validated

This is supported by decades of research across multiple weight loss contexts

Growth hormone and cell growth

J Biol Chem

Approach Phase 2b trial arm Duration 24 weeks Review Point Week 12 and 24 Notes METAOD006 (OPTIONS) used 24 weeks at oral doses 0.25, 0.5, or 1 mg/day in 502 obese adults