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doi: 10.3389/fmolb.2022.965064 Received 09 June 2022 Accepted 25 July 2022 Published 26 August 2022 Volume 9 - 2022 Edited by Guo Chen, China Pharmaceutical University, China Reviewed by Yi Wang, Sichuan Academy of Medical Sciences and Sichuan Provincial Peoples Hospital, China Xin Wang, National Institutes of Health (NIH), United States Updates Copyright 2022 Ma, Dong, Chu, Guo and Li

All center values shown are mean values, and all error bars represent standard errors of the mean (s.e.m)

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HepatoPac is a co-culture model of primary human hepatocytes and mouse fibroblasts that enable long-term hepatic metabolism and toxicity studies (Chan et al., 2019)