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Herndon and J

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After electron transfer to its substrate via the dithiol-disulfide exchange reaction, a disulfide bond is formed between Cys32 and Cys35, which is reduced by TrxR and NADPH

Following gut immune activation, activated immune cells and effector molecules such as cytokines [e.g., Interleukin-17 (IL-17), Tumor Necrosis Factor-alpha (TNF- )] can promote local inflammatory responses, alter the oral microecological environment, and either inhibit or promote the growth of specific microbial communities, playing a pivotal role in the regulation of oral microbiota (Nagao et al., 2022)

Glial cells and immature neurons are more susceptible to the free form of bilirubin than mature ones according to several investigations [21]