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The powder was then blended with water and applied to the affected parts

Study Methodology Inclusion criteria included: BMI over 25 Age between 45 to 70 years No supplement consumption in the past three months No weight loss diet in the past three months No participation in other intervention programs Willingness to lose weight No history of heart, liver, kidney disease, diabetes, hypothyroidism, rheumatoid arthritis, or surgery After signing the informed consent form, participants were randomly assigned to an intervention group (21 individuals) and a control group (22 individuals)

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Clinical data Available data included clinical check-up, semen parameters (including abstinence time, semen volume, pH, liquefaction time, sperm concentration, total sperm number, progressive sperm motility, sperm motility, and sperm morphology), sex hormone detection indicators (including serum testosterone, follicle stimulating hormone, luteinizing hormone, estradiol and prolactin), duration of infertility, routine urine test (urine leukocytes and urine red blood cells), history of ligation of internal spermatic vein, testicular volume, prostatic enlargement, history of chronic prostatitis, history of seminal vesiculitis, history of hematospermia, patient age and spouse (female) age, genetic and family histories, karyotype testing, pregnancy (including live birth, miscarriage), time to conception, and treatment costs (including examination fees, diagnostic fees, the cost of buying drugs and the cost of buying the devices of Prodom)

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