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This study suggested the extent of the angiogenic potential of the peptide is apparently very high as it appeared to extend not only on local wounds and ligaments but also on GI wounds and bone healing

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This leads to the release and cytoplasmic translocation of p53, which can subsequently activate transcription-independent pro-apoptotic signaling (Clara et al., 2024

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H.ZhangX.TangX.PuH.et al (2020)

At the same time, the brain tissue is rich in unsaturated fatty acids and transition metal ions yet has relatively fewer antioxidants comparing to other organs creating favorable conditions for oxidative damage