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Description

Enhancement of head and neck squamous cell carcinoma proliferation, invasion, and metastasis by tumor-associated fibroblasts in preclinical models

Applications include: Manufacturing of parenteral drugs and biologics

doi: 10.1248/bpb.b15-00048 91 ZhaoLGongHHuangHTuerhongGXiaH

Biotechnol Lett 32:19111914

A.HoustonJ

The Jumonji (Jmj) domain is a key catalytic module in histone demethylases, comprising N-methyl lysine and N-methyl arginine demethylases, which function as -KG-dependent oxygenases to remove methyl groups and regulate gene activity (132)