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When NNMT activity is elevated as documented in obese adipose tissue, several cancer types, and aged skeletal muscle intracellular NAD+ availability decreases, SAM availability decreases, and downstream sirtuin activity (particularly SIRT1 and SIRT3) is reduced

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Common Side Effects Mild pain or redness at the injection site Temporary dizziness Serious Side Effects Allergic reaction (rare) Swelling or breathing difficulty Serious reactions are uncommon, but you should seek medical help if symptoms worsen

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