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There were a number of different areas affected, including the central and peripheral nervous system (paraesthesia, speech and vision disorders, pins and needles sensation, chronic fatigue, anxiety, confusion, brain fog, memory loss and depression) and the musculoskeletal system (severe upper and lower limb pain, unusual neck pain, muscle weakness)

No significant differences between treatment groups were observed using the Chao1 richness estimate 42 , which accounts for ASV rareness in the richness measure (Supplementary Fig

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Dose Range: 2.515 mg weekly with 4week titration intervals

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