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Consistently, mice deficient for PKD3 in hepatocytes presented lower glucose levels when fasted for a prolonged period (Fig 5H)

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Tau-driven 26S proteasome impairment and cognitive dysfunction can be prevented early in disease by activating cAMP-PKA signaling

Notably, nsPEF can also exert cell cycle-specific effects on tumor cells, such as inhibiting the proliferation of S-phase cells without significantly affecting their viability (103)

Early studies have implicated copy number variants (CNVs), including chromosomal aneuplodies involving multiple genes, and single nucleotide variants (SNVs) in individual genes, to CAS