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It has been found that high H 2 O 2 concentrations could cause increased degradation of redox regulatory enzymes, but exact figures were not determined

Acknowledgements The authors are thankful to Integral University, Lucknow, and Eras Lucknow Medical College and Hospital, Era University, Lucknow for providing their assistance during this work

Pioglitazone promotes survival and prevents hepatic regeneration failure after partial hepatectomy in obese and diabetic KK-A(y) mice

Yes, L-glutamine degrades in complete media over time

Of note, this pathway of arginine-induced efferocytosis (with arginine derived from engulfed apoptotic cells) is complemented by efferocytosis-induced glycolysis dependent on activation of the enzyme 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 (PFKFB2), triggering enhanced binding of apoptotic cells to the macrophage cell surface via glycolysis-derived lactate (Schilperoort et al., 2023)

EECGL also blunted the HM induced generation of free radicals and lipid peroxidation in the liver and heart, indicated its direct connection with antioxidant and free radical scavenger in vivo due to the anti-oxidative property and presence of various antioxidant compounds in the EECGL via regulating the redox-homeostasis