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Around 30% of patients start with bulbar symptoms, which affect the muscles used for speaking and swallowing, leading to problems like slurred speech (dysarthria), trouble swallowing (dysphagia), and twitching of the tongue muscles (Chi et al., 2013)

Oner of the problems in the clinical use of NBDHEX may arise from its lack of specificity for GSTP1-1

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Tremelimumab is another CTLA4 mAb recently approved by the FDA in combination with durvalumab and platinum-based chemotherapy in metastatic NSCLC without EGRF and ALK gene mutations

The researchers behind it come from leading research centres, and the fact that it has been peer-reviewed and published in a reputable journal indicates that it is a serious piece of work