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To further develop therapeutic targets, we tested the efficacy of N -acetyl cysteine (NAC), an antioxidant and anti-inflammatory agent in ameliorating the extent of myocardial damage and also investigated if facilitated repair could be augmented in a rat model of left anterior descending artery ligation-induced MI

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10.1016/S0022-3476(98)70184-2 194

Adaptation through lifestyle switching sculpts the fitness landscape of evolving populations: Implications for the selection of drug-resistant bacteria at low drug pressures

We expected the resulting phenoxyl radicals to be largely reduced by GSH, in turn forming glutathionyl radicals (GS), which should be trapped as characteristic DEPMPO adducts (Fig