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Published studies have shown that NNMT expression affects myogenic differentiation the process by which satellite cells activate, proliferate, and fuse to form new muscle fibers

Moreover, the association between stressful life events and MS exacerbations suggests a complex interplay between stress, neuroinflammation, and disease progression in MS

doi: 10.1016/j.jfma.2021.04.007

These factors gradually lead to endothelial dysfunction (narrowing of the arteries) and coronary artery calcification, thus posing an increased risk for adverse cardiac events