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Knopf, D

A clinical study has shown an association between increased oxidative stress and renal proximal tubular cell injury in CKD patients with proteinuria ( Effects of the Active Ingredients From Chinese Yang/Qi-Invigorating Botanical Drugs on Mitochondrial Function and Chronic Kidney Disease To elucidate mechanisms of action, it is essential to identify the chemical components responsible for the pharmacological action(s) of Chinese Yang/Qi-invigorating tonic botanical drugs

This metabolic dependency of transformed cells on glutamine constitutes the recently defined glutamine addiction 8

Ye S, Zhou S, Ma Y, Yang J, Shi X, Zhang R, Yang Z, Peng D, Ding Z

Also, variations in protein expression involved in oxidative stress homeostasis were found, including reduced expression of NADPH oxidase and glutathione peroxidase, an increase in catalase and a decrease in protein levels involved in lipogenesis and lipolysis