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While the ability to proliferate and migrate uncontrollably is characteristic of tumor cells, glutamate has been shown to serve as a growth factor and signaling medium in certain types of tumor tissues in both an autocrine and paracrine manner (17)

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Mitochondrial dysfunction is also mediated by downregulating the expression of pathways involved in renal fibrosis such as silent information regulator two ortholog 1/peroxisome proliferator-activated receptor coactivator-1a

2 ChenI.-C.HuangI.-C.LiuM.-J.WangZ.-G.ChungS.-S.HsiehH.-L

Bu ilev sayesinde DNA ve hcredeki dier nemli protein yaplarn korur, baklk sistemini aktive eder, doku iyilemesine katkda bulunur