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Tested in 72 Sprague Dawley rats, Huannao Yicong Decoction (HYD) demonstrated superior efficacy compared to donepezil by reducing A levels, tau phosphorylation, and expression of tau protein kinase markers (TTBK1, CDK-5, GSK-3) in the hippocampal CA1 region

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Available from Nature Web site: Accessed December 17, 2015