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[3] [6] If no reversible cause is found, or when found it cannot be eliminated, lifelong vitamin B 12 administration is usually recommended

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Such studies must consider the delicate balance between suppressing pathological angiogenesis and preserving compensatory mechanisms, as emphasized by studies evaluating the use of VEGF inhibitors in the treatment of glioblastoma multiforme (Vasudev and Reynolds 2021)

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