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& Lalonde, S

Gu S, Feng H, Li X, Dong Y, Peng Y, Liu Q, et al

References Broadfield, L

Dietary glutathione protects rats from diabetic nephropathy and neuropathy. The Journal of nutrition 132.5 (2002): 897-900

This is the key observation underlying the importance ascribed to the close redox coupling of ascorbate and glutathione pools in vivo , which allows glutathione to play an indirect role in H 2 O 2 reduction as part of a reaction sequence that ultimately depends on electrons derived from NAD(P)H and/or ferredoxin (Figure 1)

PC12 cells in the A+ NAM group presented the highest degree of senescence and apoptosis following NAM treatment ( In another study, in vitro model with primary porcine brain capillary endothelial cells (pBCEC) and 3xTg AD mice