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This not only contributes to systemic inflammation but also impairs immune surveillance and responsiveness

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Precision Regenerative and Functional Medicine is a regenerative medicine practice in West Lake Hills led by Dr

10.1016/j.biomaterials.2022.121744 16 ChenY.WangZ.ZhangC.SuY.ZhouT.HuK

Of note, ROS accumulation underlies RA, and the accumulated ROS has different effects over different cell types

Mechanistically, several ADCs have been shown to induce ICD, characterized by the release of DAMPs, which promote dendritic cell activation, antigen cross-presentation, and subsequent priming of tumor-specific T cells [117]