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These findings align with previous studies showing that GPX4 undergoes a rapid decline in IIRI models, suggesting that lipid peroxides eventually impair GPX4 expression [8]

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this pathway has been shown to impair process outgrowth in neurons and regulate glycolysis - the major source of of ATP in mature OLs which contributes to protein and lipid production needed for myelin biosynthesis

Apparently, ferroptosis promotes ERS and cardiomyocytes injury, and aggravates the progression of Cardiac Diseases

doi: 10.3389/fimmu.2024.1374581 Received 22 January 2024 Accepted 16 February 2024 Published 08 March 2024 Volume 15 - 2024 Edited by Ruben Dario Motrich, National Scientific and Technical Research Council (CONICET), Argentina Reviewed by Jelka Pohar, National Institute of Biology (NIB), Slovenia Shahnawaz Jadeja, University College Dublin, Ireland Updates Copyright 2024 Ishimoto, Arakawa, Vural, Sthr, Vollmer, Galinski, Siewert, Rhl, Poluektov, Delcommenne, Horvath, He, Summer, Pohl, Alharbi, Dornmair, Arakawa and Prinz

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