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Measurable reduction in gingival inflammation is typically observed within 48 weeks when combined with professional periodontal care

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16 Mechanism of Action Current medical therapies A multimodal approach is required to manage CKD and typically involves a combination of fluids to maintain hydration (encouraging drinking, subcutaneous fluid therapy), nutritional support through the diet (moderate protein, restricted phosphate and potassium supplementation), anti-hypertensives, anti-proteinurics, phosphate binders, anti-emetics and antacids

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The behaviour of the rodent whilst in the maze is often recorded remotely using a video camera so as not to interfere with the trials