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Source Data Figure 3 (download PPTX Raw immunofluorescence tissue section images and raw hematoxylin and eosin stained tissue section images (raw, uncropped versions embedded in file)

Mitapivat treatment of 4.2 / mice significantly reduced liver iron overload as documented by both Perls staining and liver iron concentration (Figure 5, A and B)

For the New York State and Centers for Disease Control and Prevention Multisystem Inflammatory Syndrome in Children Investigation Team

Bains A, Chawla P, Kaur S, Najda A, Fogarasi M, Fogarasi S

n = 6 independent biological replicates per group

Side effects can include flushing, nausea, headache, and transient blood pressure changes