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Science 277 , 11091113 (1997) Schuller, U

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Thyroid hormones, particularly triiodothyronine (T3) and thyroxine (T4), are transported across the bloodbrain barrier (BBB) by specialized carriers and are metabolically activated or inactivated by local deiodinase enzymes ( Current therapeutic paradigms focus primarily on pharmacological hormone replacement, most commonly levothyroxine (27)

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