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We thank Karen Adelman, Sudha Biddinger, Mitchell Guttman, Evan Rosen, and Richard Young for serving on the PhD Dissertation Advisory Committee of XYL at Harvard University

Data were expressed as mean standard deviation, and the significance of differences between group was reflected by the P-value

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Chang, JY, Mehran, RJ, Feng, L, Verma, V, Liao, Z, Welsh, J, Lin, SH, O'Reilly, M, Jeter, M, Balter, PA, McRae, SE, Berry, D, Heymach, JV, Roth, JA, Antonoff, MB, Hofstetter, WL, Rajaram, R, Rice, DC, Sepesi, B, Swisher, SG , Vaporciyan, AA, Walsh, GL, DeGraaf, C, Correa, AM, Chen, A, Gandhi, S, Komaki, R, Lee, PP, Nguyen, Q, Ning, M, Gao, S, Pollard-Larkin, JM, Nitsch, PL, Sadagopan, R, Wang, X

14 These widespread benefits stem from GH and IGF-1's systemic effects, leading to variable individual responses