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Cells were cultured in Dulbeccos Modified Eagles Medium (DMEM) (Cytiva, SH30022.01) with 10% Fetal Bovine Serum (FBS) (Thermo Fisher Scientific, A5256701) and 1% Penicillin-Streptomycin (P/S) (Beyotime, C0222) solution, and were maintained at 37 C in a humidified incubator with 5% CO 2

Discussion This study demonstrates that the small-molecule PCSK9 inhibitor SBC-115,076 alleviates AD-like pathology in an AlCl-induced zebrafish larval model

ACL Return-to-Sport Acceleration

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TP is supported by grants from the NIH (R21AG072205, R21AI097745, R01CA214913, R01HL128168, R01CA284372, and R01CA284603), US Department of Defense Peer Reviewed Medical Research Program (HT94252410100), Koch Institute-Dana Farber/Harvard Cancer Center Bridge Grant and the Rullo Family MGH Research Scholar Award