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Exploiting bacterial DNA gyrase as a drug target: current state and perspectives

Two flavoenzymes catalyze the post-translational generation of 5-chlorotryptophan and 2-aminovinyl-cysteine during NAI-107 biosynthesis

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A 2-year study of 100 patients with vitiligo, who were treated with oral folic acid (5 mg) and VitB12 (1 mg) in combination with sunlight exposure and UVB radiation, showed re-pigmentation in 52 participants with stable and progressive vitiligo