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IDH2 deficiency impairs mitochondrial function in endothelial cells and endothelium-dependent vasomotor function

[DOI] [PubMed] [Google Scholar] 15.Kranner I, Birti S, Anderson KM, Pritchard HW

The risk factors for brain cancer are genetic factors such as gene mutations, genetic ancestry, and telomere length, demographic factors, namely age, sex, race/ethnicity, and socioeconomic status, and non-genetic risk factors, including allergies, anthropometric factors, head injury, diet, ionizing radiation, organic solvents, smoking, viral infection, structural birth defects, and birth weight etc [50,51,52,53,54,55,56,57]

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Tokarew JM, El-Kodsi DN, Lengacher NA, Fehr TK, Nguyen AP, Shutinoski B, ONuallain B, Jin M, Khan JM, Ng ACH, Li J, Jiang Q, Zhang M, Wang L, Sengupta R, Barber KR, Tran A, Im DS, Callaghan S, Park DS, Zandee S, Dong X, Scherzer CR, Prat A, Tsai EC, Takanashi M, Hattori N, Chan JA, Zecca L, West AB, Holmgren A, Puente L, Shaw GS, Toth G, Woulfe JM, Taylor P, Tomlinson JJ, Schlossmacher MG (2021) Age-associated insolubility of parkin in human midbrain is linked to redox balance and sequestration of reactive dopamine metabolites