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Although these proteins differ in sequence from A, they can trigger pathogenic mechanisms related to AD, promoting amyloid plaque deposition and facilitating A fibril and oligomer misfolding

Their proteomic profiles vary significantly depending on the plant source and the biogenesis pathway involved

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69,70 Patients in a phase 2 clinical trial employing curcumin in 21 patients with advanced pancreatic cancer demonstrated clinical indications of tumor regression after receiving 8 g/day of curcumin orally for 8 weeks

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