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Pharmacological or CR-induced inhibition of mTORC1 in mice selectively reduces LIP-protein synthesis and thereby increases the LAP/LIP ratio in different tissues, which is associated with metabolic improvements resembling CR (Albert & Hall, 2015

114 In a controlled study enrolling 20 participants who received the VLCKD, a significant improvement in biochemical parameters was observed after 8 weeks of KD adherence, which included a reduction in BMI, LDL-C, TGs, insulinemia, and liver transaminases