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A number of currently available ferroptosis modulators also face limitations in drug-like properties, such as poor water solubility, instability and suboptimal pharmacokinetics, which hinder their development into clinically viable agents (141)

LncRNA WAC-AS1 Recent studies have found that ferroptosis can spread widely in the renal tissue microenvironment in a wavy form, forming a ferroptosis wave that results in extensive renal tubule necrosis and aggravates renal I/R injury

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Crystal structures of the reduced, sulfenic acid, and mixed disulfide forms of SarZ, a redox active global regulator in Staphylococcus aureus

Schulz JB, Lindenau J, Seyfried J, Dichgans J

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