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When iron levels become insufficient, follicles prioritize essential bodily functions over hair growth, leading to follicle miniaturization and eventual hair loss

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Lowering protein by an average of 0.72 grams per kilogram of body weight per day resulted in an average decrease of 25% in IGF-1 (30)

Receptor Downregulation Findings and Study Design Implications A well-documented finding in the research literature is that continuous IGF-1 receptor activation leads to receptor downregulation after approximately four to six weeks, reducing cellular responsiveness to further stimulation

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