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Description

This series of reactions highlights how normal cellular respiration inadvertently contributes to oxidative stress

Salvio G, Ciarloni A, Cordoni S, Cutini M, Delli Muti N, Finocchi F

Previous studies in neurodegenerative diseases such as Alzheimer's and Parkinson's have demonstrated that both Hcy and its active derivative, homocysteine thiolactone (HTL), accumulate with age in the brain[16, 18]

2016 Jul;96:130-8.

The prefrontal cortex was selected for molecular analysis due to its key involvement in emotional regulation, cognitive control, and extinction of fear responses, which are central to PTSD pathology