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Endosomal Toll-like receptors (TLR3 and TLR7) bind to ssRNA in the endosome, while components of the inflammasome such as MDA5, RIG-I, NOD2 and PKR bind to ssRNA and dsRNA in the cytosol, resulting in cellular activation, and production of type I interferon and multiple inflammatory mediators 7 (Fig

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Other Penalties: The driver will also face penalties similar to a standard VC 23152(b) offense for a first-time misdemeanor DUI, including: Jail time of up to 12 months