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Gigante B Article: EUROPEAN JOURNAL OF AGEING

Last reviewed: June 1, 2026 Last updated: June 1, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

Regulation of HippoYAP signaling axis by Isoalantolactone suppresses tumor progression in cholangiocarcinoma

20,000 cells were plated in a 96-well plate for 24 h at 37 C

This work is supported via funding from Prince Sattam bin Abdulaziz University project number (PSAU/2025/R/1446) and Researchers Supporting Project number (MHIRSP2025006), AlMaarefa University, Riyadh, SaudiArabia

In marine organisms and some human pathogens, this enzyme fulfills the function of a sulphoxide synthase catalyzing the first step in ovothiol A biosynthesis to generate an unmethylated sulphur-containing thiohistidine precursor of this metabolite 41,42