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Then, solution was brought to total volume of 10 mL by adding 8.7 mL of milliQ water (solution color will turn to dark orange immediately and will turn gradually to colorless with time)

Raman spectra were explored with a Scientific LabRAM HR Evolution Raman spectrometer (HORIBA, Japan) equipped with a 532 nm laser

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Cellular component Both the total identified proteins and the differentially expressed proteins were mainly enriched for the GO terms associated with cell part, intracellular part, and organelle

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