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Effective inhibition of HIF-1 may significantly increase the efficacy of radiotherapy and chemotherapy by increasing radiosensitivity and chemosensitivity of tumor cells and also by upregulating anti-tumor immunity

Subsequently, the expression of pro-inflammatory cytokines is activated, and these are then also contributing to pyroptosis [59]

These nutrients are key components of cell membranes and also function as signaling molecules in inflammatory processes (177)

The above results would collectively suggest that BoCA, in part, leads to gut microbiome reorganization, which increased gut-host production of PAGln

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We stick to the principle of "quality first, service first, continuous improvement and innovation to meet the customers" for the management and "zero defect, zero complaints" as the quality objective