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The two enzymes, phenylalanine ammonia-lyase 1 (PAL1) and isochorismate synthase 1 (ICS1), are the key enzymes in the SA synthesis pathway

One research suggested that mean plasma estradiol concentrations may be higher in pre-menopausal women than in controls but were found not statistically significant in either of these studies [23]

Although the thyroid gland is not the organ that has the most significant overall amount of Se in the human body, it does have the highest concentration of Se among all endocrine organs and, in fact, among all tissues regarding the amount of Se that it contains per gram [9]