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Characterization of the effect of pomegranate crude extract, and its post-harvesting preservation procedures, on redox tone, cellular growth and metabolic profile of MDA-MB-231 cell line

When this ratio shifts, it is often a sign that the body is working harder to manage oxidative stress

Ototoxicity and irreversible hearing impairment In addition to peripheral neuropathy, long-term platinum accumulation in cochlear tissues is the core driver of delayed, irreversible post-chemotherapy ototoxicity

Its underlying mechanisms are multifaceted, encompassing genetic variations, environmental influences, cerebral artery constriction, abnormalities in monoamine neurotransmitters, oxidative stress, mitochondrial disturbances, the involvement of calcitonin gene-related peptide (CGRP), neurogenic inflammation, and broader neuroinflammation (6)

10.1146/annurev-nutr-071812-161246 Annu Rev Nutr

The peptide's interaction with growth factor signalling pathways and its influence on wound healing cascades continue to be active areas of investigation in preclinical studies