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The conversion from homocysteine to cystathionine by cystathionine -synthase (CBS) is described to be a key player in restoring intracellular cysteine pool as decreasing its expression increases sensitivity to ferroptosis in ovarian cancer cells upon erastin treatment (54)

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Additionally, at least a quarter of adults were found to consume less than the average estimated requirement published by the United States and Canada, which suggests that diseases such as Alzheimer's disease, ischemic heart disease and osteoporosis are linked to a low intake of copper (96)

DOI:10.1096/fj.201903119R Tiedge M., Lortz S., Drinkgern J., Lenzen S

We found that the levels of CXCL10 and its downstream effectors, p-JNK, COL1A1, and p-AKT, significantly increased in M38 or B16 group, WCV significantly reduced their levels close to control in VM38 or VB16 group, and PD-1 had no obvious impacts in PM38 or PB16 group (Fig