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Comparing H2 Blockers to PPIs in B12 Depletion H2 receptor antagonists and proton pump inhibitors (PPIs) both reduce stomach acid

Previous work has reported relatively increased Firmicutes and Proteobacteria and decreased Bacteroidetes in mice on an HFD, regardless of concomitant obesity (weight gain was minimized using a RELM knockout mouse 78 ) 78,79