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Toxins 15:15020085

2015;10: e0123210

Diverging consequences of hexosamine biosynthesis in cardiovascular disease

Giblin FJ

414 YangMSoKFLamWCLoACY

A plausible explanation for this association is that excessive amino acid concentrations result in aberrant activation of the insulin signaling pathway, which, in turn, interferes with glucose uptake and metabolism (14, 17, 53, 55, 56)