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After condensation with dicyclohexylcarbodiimide (DCC) was removed the Ddz protection group in each step with 5% TFA in dichloromethane, following by washing and deprotonation with 10% triethylamine in dichloromethane

Originally discovered in the 1970s, DSIP is a neuropeptide linked to the regulation of sleep cycles, stress response, and even hormone release

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Modern lifestyle habits have significantly increased risk factors for both deficiencies