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Description

17 alpha-estradiol exerts neuroprotective effects on SK-N-SH cells

Contrary to macrophage, vascular endothelial cells are lack CAT but high in SOD 62 , implying that much less intracellular ROS would be produced when these cells encountered the -3 PUFA droplets

Nat Genet 2000, 26: 379-382

Moreover, multiple signaling pathways are involved in regulating intestinal epithelial cell apoptosis, leading to barrier disruption

In conclusion, TCM exhibits substantial potential for both research and clinical application in AD by targeting and attenuating the ferroptosis pathway, offering promising avenues for disease modification and symptomatic relief