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Liver regeneration after acetaminophen hepatotoxicity: Mechanisms and therapeutic opportunities

A 2.5 mg dose now requires 33.3 units instead of 25

Three minutes post injection, mice were sacrificed by cervical dislocation

Neuropsychopharmacology 31 , 23952404 (2006)

Leflunomide has shown clinical, functional, and structural efficacy similar to MTX 88,89 and has also been used effectively in combination with biological agents