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Previously, two other coronaviruses, namely, SARS-CoV and Middle East respiratory syndrome coronavirus (MERS-CoV), surfaced in the years 2002 and 2012 respectively, leading to a lethal respiratory diseases in humans [3]

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Indeed, as of 2024, the 10th-ranked disease, GVHD, had only seven DHT-enabled trials, suggesting that this focus is sufficient to capture key trends

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With a deeper understanding of its mechanistic underpinnings and the deployment of innovative diagnostic and therapeutic tools, there is a tangible opportunity to protect vulnerable populations, reduce renal disease burden, and build resilient health systems against environmental toxicants

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